Inflammation has to fight pathogens fast—but it can't get out of control. Researchers at the German Cancer Research Center ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

CLASSIC enables large-scale testing of complex DNA circuits in human cells, advancing data-driven synthetic biology.

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Since the publication of the Human Genome Project, researchers have expanded the field of genomics to probe deeper into the underpinnings of human biology and disease, including studies of the body’s ...

Not all stressors have the same impact on health. Stress arising from threats to social safety is most likely to affect psychological, biological, and clinical outcomes. This is the conclusion UCLA ...